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The great advantage to having a single database is the ability to search. Since UR cannot search multiple databases in one go, this should be your primary consideration.
I have two databases. One is for my email archive, the other is for everything else. I found that when a folder has thousands of items, it can slow the loading of the database if the folder is left open when the database is last used. Opening the folder will also take some time. I work around this by creating sub-folders and placing hundreds of items in each one. For example, my 2007 email archive has almost 90,000 emails (yes, this is work related - no spam, junk, etc.). The folder took foreevr to open, so it is now broken down by month. Much faster. Searching speed for this database is slower, but not unreasonable. I also use a dedicated program, Mailbag Assistant, for this purpose too, but each has its strengths.
By the way, the size of the email database is 8.5GB; my other database is a more reasonable 673MB.
I wrote this quickly - does this help?
Jon
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